2021 season
Week 1
All 16 games are final — open any matchup for the full breakdown.
Week 1Thu, Sep 9, 2021
Dallas Cowboys29
Tampa Bay BuccaneersWin31
TB -10 no coverO 52.5 ✓One-score finish
Raymond James StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Arizona CardinalsWin38
Tennessee Titans13
TEN -2.5 upsetU 54 ✓Blowout
Nissan StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Jacksonville Jaguars21
Houston TexansWin37
JAX -3.5 upsetO 45.5 ✓Dome
NRG StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Los Angeles ChargersWin20
Washington Commanders16
WAS -2.5 upsetU 45.5 ✓
FedExFieldBreakdown →
Week 1Sun, Sep 12, 2021
Minnesota Vikings24
Cincinnati BengalsWin27
MIN -3 upsetO 47 ✓One-score finish15 mph wind
Paul Brown StadiumBreakdown →
Week 1Sun, Sep 12, 2021
New York Jets14
Carolina PanthersWin19
CAR -3.5 ✓U 44.5 ✓
Bank of America StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Philadelphia EaglesWin32
Atlanta Falcons6
ATL -3.5 upsetU 49 ✓Blowout
Mercedes-Benz StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Pittsburgh SteelersWin23
Buffalo Bills16
BUF -6.5 upsetU 48 ✓17 mph wind
New Era FieldBreakdown →
Week 1Sun, Sep 12, 2021
Seattle SeahawksWin28
Indianapolis Colts16
SEA -3 ✓U 49 ✓Dome
Lucas Oil StadiumBreakdown →
Week 1Sun, Sep 12, 2021
San Francisco 49ersWin41
Detroit Lions33
SF -9.5 no coverO 46 ✓ShootoutDome
Ford FieldBreakdown →
Week 1Sun, Sep 12, 2021
Cleveland Browns29
Kansas City ChiefsWin33
KC -5.5 no coverO 54.5 ✓Shootout
GEHA Field at Arrowhead StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Denver BroncosWin27
New York Giants13
DEN -3 ✓U 41.5 ✓19 mph wind
MetLife StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Green Bay Packers3
New Orleans SaintsWin38
GB -4 upsetU 49 ✓Blowout
TIAA Bank StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Miami DolphinsWin17
New England Patriots16
NE -3.5 upsetU 43.5 ✓One-score finish15 mph wind
Gillette StadiumBreakdown →
Week 1Sun, Sep 12, 2021
Chicago Bears14
Los Angeles RamsWin34
LA -9.5 ✓O 46 ✓Dome
SoFi StadiumBreakdown →
Week 1Mon, Sep 13, 2021
Baltimore Ravens27
Las Vegas RaidersWin33
BAL -3 upsetO 50.5 ✓ShootoutDome
Allegiant StadiumBreakdown →